4-NITRO-O-PHENYLENEDIAMINE
HAIR DYEING · CAS 99-56-9 · EC 202-766-3
Chemical identification
- INCI
- 4-NITRO-O-PHENYLENEDIAMINE
- Chemical name
- 4-nitro-o-phenylenediamine (CI 76020)
- IUPAC
- 4-Nitro-1,2-phenylenediamine
- CAS
- 99-56-9
- EC / EINECS
- 202-766-3
- Trade synonyms
- —
EU regulatory status
- Reference
- III/240
- Maximum concentration
- —
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5%
- Warnings
- To be printing on the label: Hair colorants can cause severe allergic reactions.
- CMR
- Not classified
- Last CosIng update
- 2013-09-09
Recent analyses mentioning this ingredient
Sin análisis publicados todavía para este ingrediente.
Other Annex III items
- 1,3-BIS-(2,4-DIAMINOPHENOXY)PROPANE
- 1,5-NAPHTHALENEDIOL
- 1-HEXYL 4,5-DIAMINO PYRAZOLE SULFATE
- 1-NAPHTHOL
- 2,4-DIAMINOPHENOXYETHANOL HCL
- 2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE
- 2,6-DIAMINOPYRIDINE
- 2,6-DIHYDROXY-3,4-DIMETHYLPYRIDINE
Technical function
This ingredient is classified as:
About Annex III of Regulation (EC) No 1223/2009
Annex III of Regulation (EC) No 1223/2009 lists the substances that may be used in cosmetic products only under specific conditions defined by the European legislator. For each entry, the annex establishes the maximum permitted concentration, the product categories in which use is authorised (rinse-off or leave-on, use on children, etc.), the applicable additional conditions, and the mandatory labelling warnings that the manufacturer must include. A prior safety assessment by the SCCS is a prerequisite for any modification to this list. Restrictions may vary depending on the area of application — hair, skin, mucous membranes — and the target population — adults, children under three years of age. BD-API allows Responsible Persons to verify in real time whether their formulations comply with the current conditions of Annex III, integrating CosIng information into their audit workflows. Explore the full Annex III →
Restriction conditions like these change
A new maximum concentration or product-type condition turns a compliant formula into a non-compliant one overnight. BD-API delivers every Annex III change to your system via API, webhooks and automated alerts.
Data source: Official CosIng from the European Commission, updated on 9 April 2026. Learn more →