RestrictedAnx. IIIRef. III/221

HYDROXYETHYL-2-NITRO-P-TOLUIDINE

HAIR DYEING · CAS 100418-33-5 · EC 408-090-7

Chemical identification

INCI
HYDROXYETHYL-2-NITRO-P-TOLUIDINE
Chemical name
1-Methyl-3-nitro-4-(.beta.-hydroxyethyl)aminobenzene
IUPAC
2-(4-Methyl-2-nitroanilino)ethanol
CAS
100418-33-5
EC / EINECS
408-090-7
Trade synonyms
84433 · 87633

EU regulatory status

Reference
III/221
Maximum concentration
(b) 1,0%
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1,0% For (a) and (b): - Do not use with nitrosating agents - Maximum nitrosamine content 50 microgram/Kg - Keep in nitrite-free containers
Warnings
To be printed on the label: Hair colorants can use severe allergic reactions
CMR
Not classified
Last CosIng update
2013-09-09

Recent analyses mentioning this ingredient

Sin análisis publicados todavía para este ingrediente.

Technical function

This ingredient is classified as:

HAIR DYEING

About Annex III of Regulation (EC) No 1223/2009

Annex III of Regulation (EC) No 1223/2009 lists the substances that may be used in cosmetic products only under specific conditions defined by the European legislator. For each entry, the annex establishes the maximum permitted concentration, the product categories in which use is authorised (rinse-off or leave-on, use on children, etc.), the applicable additional conditions, and the mandatory labelling warnings that the manufacturer must include. A prior safety assessment by the SCCS is a prerequisite for any modification to this list. Restrictions may vary depending on the area of application — hair, skin, mucous membranes — and the target population — adults, children under three years of age. BD-API allows Responsible Persons to verify in real time whether their formulations comply with the current conditions of Annex III, integrating CosIng information into their audit workflows. Explore the full Annex III

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Data source: Official CosIng from the European Commission, updated on 9 April 2026. Learn more →