Chemical identification
- INCI
- THIMEROSAL
- Chemical name
- Mercurate(1-), ethyl[2-mercaptobenzoato(2-)-O, S]-, sodium
- IUPAC
- —
- CAS
- 54-64-8
- EC / EINECS
- 200-210-4
- Trade synonyms
- 28141
EU regulatory status
- Reference
- V/16
- Maximum concentration
- 0.007% (of Hg) If mixed with other mercurial compounds authorized by this Regulation, the maximum concentration of Hg remains fixed at 0.007%
- Other conditions
- —
- Warnings
- Contains Thiomersal
- CMR
- Not classified
- Last CosIng update
- 2010-10-16
Recent analyses mentioning this ingredient
- CríticoAsesoramiento científico SCCS — Conservantes con mercurio · 10 de febrero de 2026SCCS - Scientific Advice on the safety of Thiomersal (CAS No. 54-64-8, EC No. 200-210-4) and Phenylmercuric salts as preservatives in cosmetic products
El SCCS emitió su asesoramiento final (SCCS/1686/25, adoptado 2 febrero 2026) sobre Thiomersal (CAS 54-64-8) y sales de Fenilmercúrico como conservantes en cosméticos oculares: concluye que su uso NO es seguro al máximo actualmente autorizado (0.007% en Hg), ya que el Margen de Seguridad para nefrotoxicidad es menor a 100 y la genotoxicidad no está resuelta. Las empresas que usen estos conservantes en delineadores, rímel, soluciones limpiadores de ojos u otros productos oculares deben iniciar urgentemente la búsqueda de alternativas, ya que se anticipa la modificación o derogación de las entradas 16 y 17 del Anexo V del Reglamento 1223/2009.
Other Annex V items
- 2-BROMO-2-NITROPROPANE-1,3-DIOL
- 5-BROMO-5-NITRO-1,3-DIOXANE
- 7-ETHYLBICYCLOOXAZOLIDINE
- BENZETHONIUM CHLORIDE
- BENZYL ALCOHOL
- BENZYLHEMIFORMAL
- BROMOCHLOROPHENE
- CHLOROBUTANOL
Technical function
This ingredient is classified as:
About Annex V of Regulation (EC) No 1223/2009
Annex V of Regulation (EC) No 1223/2009 lists the preservatives authorised for use in cosmetic products in the European Union. Only preservatives included in this annex may be used to inhibit the development of micro-organisms in cosmetics. Each entry defines the maximum permitted concentration, the product categories in which it may be used, the applicable specific conditions, and any mandatory labelling warnings. Modifications to this annex are published periodically in the Official Journal of the EU following an opinion from the SCCS (Scientific Committee on Consumer Safety) and are automatically reflected in this database. BD-API synchronises these updates on a continuous scheduled basis and allows manufacturers and Responsible Persons to verify in real time whether their formulations comply with the current conditions of Annex V, integrating CosIng information into their audit and quality control workflows. Explore the full Annex V →
Positive lists are tightly governed
New SCCS opinions and amending regulations reshape this Annex regularly — an entry that changes must be reflected in your active formulations. BD-API delivers every change to your system via API, webhooks and automated alerts.
Data source: Official CosIng from the European Commission, updated on 9 April 2026. Learn more →