Anx. II
Prohibited substances in cosmetics — Annex II of EU Regulation 1223/2009
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About Annex II
Annex II of Regulation (EC) No 1223/2009 lists the substances whose use is expressly prohibited in cosmetic products placed on the European Union market. Inclusion in this annex results from the scientific assessment of the Scientific Committee on Consumer Safety (SCCS), which determines that the substance cannot be used safely in any cosmetic product regardless of concentration or category of use. Once the prohibition is published in the Official Journal of the EU through a Commission Regulation, manufacturers and Responsible Persons are given a transitional period to withdraw non-compliant products from the market. The CosIng database, maintained by the European Commission, updates this list periodically. BD-API synchronises these updates automatically and notifies connected systems via signed webhooks, ensuring that cosmetic formulations are always audited against the most recent version of the annex.
Not sure how to interpret the columns (Ref. No., Max conc.)? → Guide: how to read the annexes step by stepIngredients of Annex II(first 100 of 1,758)
| Name | Function(s) | Ref. No. | Max conc. |
|---|---|---|---|
| (+/-)-2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propyl-1,1,2,2-tetrafluoroethylether (Tetraconazole - ISO) | — | 1001 | — |
| (+/-)-Tetrahydrofurfuryl -(R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate (Quizalofop-P-tefuryl - ISO) | — | 755 | — |
| (1,3,4,5,6,7-Hexahydro-1,3-dioxo-2H-isoindol-2-yl)methyl (1R-trans)-2,2-dimethyl-3-(2- methylprop-1-enyl)cyclopropanecarboxylate | — | 1619 | — |
| (1R,4S,5R,8S)-1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene (Isodrin-ISO) | — | 198 | — |
| (1R,4S,5R,8S)-1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethanonaphthalene (endrin - ISO) | — | 196 | — |
| (2-Acetoxyethyl)trimethylammonium hydroxide (Acetylcholine) and its salts | — | 2 | — |
| (2-Chloroethyl)(3-hydroxypropyl)ammonium chloride | — | 1515 | — |
| (2-Isopropylpent-4-enoyl)urea (apronalide) | — | 216 | — |
| (29H,31H-Phthalocyaninato(2-)-N29,N30,N31,N32)copper (Pigment Blue 15; CI 74160) when used as a substance in hair dye products | — | 1367 | — |
| (2RS,3RS)-3-(2-Chlorophenyl)-2-(4-fluorophenyl)-[1H-1,2,4-triazol-1-yl)methyl]oxirane; Epoxiconazole | — | 663 | — |
| (3-Chloro-2-hydroxypropyl) trimethylammonium chloride | — | 1510 | — |
| (3-Chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone | — | 1085 | — |
| (4-Ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane | — | 1409 | — |
| (4-Hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride | — | 1106 | — |
| (4-Phenylbutyl)phosphinic acid | — | 1413 | — |
| (5-chloro-2-methoxy-4-methyl-3-pyridyl)(4,5,6-trimethoxy-o-tolyl)methanone; pyriofenone | — | 1683 | — |
| (6-(4-Hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazine-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate | — | 757 | — |
| (6R-trans)-1-((7-Ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide | — | 1524 | — |
| (8-[(4-Amino-2-nitrophenyl)azo]-7-hydroxy-2-naphthyl)trimethylammonium and its salts, (except Basic Red 118 as impurity in Basic brown 17), when used as a substance in hair dye products | — | 1291 | — |
| (E)-3-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol | — | 1475 | — |
| (Epoxyethyl)benzene (Styrene oxide) | — | 656 | — |
| (Methyl-ONN-azoxy)methyl acetate | — | 728 | — |
| (Methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'-dipyridinium dichloride dihydrochloride | — | 1155 | — |
| (micro-((7,7'-Iminobis(4-hydroxy-3-((2-hydroxy-5-(N-methylsulphamoyl)phenyl)azo)naphthalene-2-sulphonato))(6-)))dicuprate and its salts, when used as a substance in hair dye products | — | 1268 | — |
| (R)-5-Bromo-3-(1-methyl-2-pyrrolidinylmethyl)-1H-indole | — | 1197 | — |
| (R)-alpha-Phenylethylammonium (-)-(1R,2S)-(1,2-epoxypropyl)phosphonate monohydrate | — | 1053 | — |
| (R,S)-2-Amino-3,3-dimethylbutane amide | — | 1522 | — |
| (RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate; tolpyralate | — | 1684 | — |
| (S)-2,3-Dihydro-1H-indole-carboxylic acid | — | 1104 | — |
| (Z)-2-Methoxymino-2-[2-(tritylamino)thiazol-4-yl]acetic acid | — | 1489 | — |
| 1,1,2-Trichloroethane | — | 1169 | — |
| 1,1,3,3,5-Pentamethyl-4,6-dinitroindane (Moskene) | — | 421 | — |
| 1,1-Bis(dimethylaminomethyl)propyl benzoate (amydricaine, alypine) and its salts | — | 143 | — |
| 1,2,3,4,5,6-Hexachlorocyclohexane (BHC-ISO) | — | 195 | — |
| 1,2,3-Trichloropropane | — | 1141 | — |
| 1,2,4-Benzenetriacetate and its salts, when used as a substance in hair dye products | — | 1254 | — |
| 1,2,4-Triazole | — | 1056 | — |
| 1,2,4-Trihydroxybenzene when used as a substance in hair and eyelash dye products | — | 1642 | — |
| 1,2-Benzenedicarboxylic acid, di-C7-11-branched and linear alkyl esters | — | 1153 | — |
| 1,2-Benzenedicarboxylic acid, dihexyl ester, branched and linear | — | 1583 | — |
| 1,2-Benzenedicarboxylic acid, dipentylester, branched and linear [1]; n-Pentyl-isopentylphthalate [2]; di-n-Pentyl phthalate [3]; Diisopentylphthalate [4] | — | 1151 | — |
| 1,2-Benzenedicarboxylic acid; di-C6-8-branched alkylesters, C7-rich | — | 1485 | — |
| 1,2-Bis(2-methoxyethoxy)ethane; Triethylene glycol dimethyl ether; (TEGDME); triglyme | — | 1147 | — |
| 1,2-Dibromo-3-chloropropane | — | 646 | — |
| 1,2-Dibromoethane | — | 651 | — |
| 1,2-Dichloropropane; propylene dichloride | — | 1625 | — |
| 1,2-Diethoxyethane | — | 1472 | — |
| 1,2-Dihydroxyanthraquinone (Pigment Red 83; CI 58000) when used as a substance in hair dye products | — | 1361 | — |
| 1,2-Epoxy-3-phenoxypropane (Phenylglycidyl ether) | — | 659 | — |
| 1,2-Epoxy-4-epoxyethylcyclohexane; 4-vinylcyclohexene diepoxide | — | 1469 | — |
| 1,2-Epoxybutane | — | 400 | — |
| 1,3,5-triazine-2,4,6-triamine; melamine | — | 1711 | — |
| 1,3,5-Trihydroxybenzene (Phloroglucinol) and its salts, when used as a substance in hair dye products | — | 1253 | — |
| 1,3,5-Tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione (TGIC) | — | 741 | — |
| 1,3,5-tris-[(2S and 2R)-2,3-Epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione | — | 760 | — |
| 1,3-Benzenediamine, 4-methyl-6-(phenylazo)- and its salts, when used as a substance in hair dye products | — | 1294 | — |
| 1,3-Bis(vinylsulfonylacetamido)propane | — | 1202 | — |
| 1,3-Dichloropropan-2-ol | — | 648 | — |
| 1,3-Dimethylpentylamine and its salts | — | 30 | — |
| 1,3-Diphenylguanidine | — | 993 | — |
| 1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline (Solvent Yellow 33; CI 47000) when used as a substance in hair dye products | — | 1358 | — |
| 1,3-Propanesultone | — | 751 | — |
| 1,4,5,8-Tetraaminoanthraquinone (Disperse Blue 1) | — | 700 | — |
| 1,4-Benzenediamine, N,N’-mixed Ph and tolyl derivs. | — | 1746 | — |
| 1,4-bis(p-Tolylamino)anthraquinone (Solvent Green 3; CI 61565) when used as a substance in hair dye products | — | 1364 | — |
| 1,4-Diamino-2-methoxy-9,10-anthracenedione (Disperse Red 11) and its salts, when used as a substance in hair dye products | — | 1301 | — |
| 1,4-dichloro-2-nitrobenzene | — | 1760 | — |
| 1,4-Dichlorobenzene (p-Dichlorobenzene) | — | 1173 | — |
| 1,4-Dichlorobut-2-ene | — | 654 | — |
| 1,4-Dihydroxy-5,8-bis[(2-hydroxyethyl)amino]anthraquinone (Disperse Blue 7) and its salts, when used as a substance in hair dye products | — | 1302 | — |
| 1,4-Dihydroxybenzene (Hydroquinone), with the exception of entry 14 in Annex III | — | 1339 | — |
| 1,7-Naphthalenediol, when used as a substance in hair dye products | — | 1228 | — |
| 1-((4-Phenylazo)phenylazo)-2-naphthol (Solvent Red 23; CI 26100) when used as a substance in hair dye products | — | 1353 | — |
| 1-(1-Naphthylmethyl)quinolinium chloride | — | 1196 | — |
| 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride | — | 1474 | — |
| 1-(4-Chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1-ylmethyl)pentan-3-ol | — | 1189 | — |
| 1-(4-Methoxyphenyl)-1-pentene-3-one (alpha-Methylanisylideneacetone), when used as a fragrance ingredient | — | 444 | — |
| 1-[(2-Chloro-4-nitrophenyl)azo]-2-naphthol (Pigment Red 4; CI 12085) and its salts when used as a substance in hair dye products | — | 1345 | — |
| 1-[(3-Aminopropyl)amino]-4-(methylamino)anthraquinone and its salts, when used as a substance in hair dye products | — | 1303 | — |
| 1-Amino-4-(methylamino)-9,10-anthracenedione (Disperse Violet 4) and its salts, when used as a substance in hair dye products | — | 1283 | — |
| 1-Amino-4-[[4-[(dimethylamino)methyl]phenyl]amino]anthraquinone and its salts, when used as a substance in hair dye products | — | 1278 | — |
| 1- and 2-Naphthylamines and their salts | — | 242 | — |
| 1-Bromo-2-methylpropyl propionate | — | 1495 | — |
| 1-Bromo-3,4,5-trifluorobenzene | — | 1017 | — |
| 1-Bromopropane; n-Propyl bromide | — | 1139 | — |
| 1-Butyl-3-(N-crotonoylsulphanilyl)urea | — | 108 | — |
| 1-Chloro-2,3-epoxypropane (Epichlorohydrin) | — | 657 | — |
| 1-Chloro-4-nitrobenzene | — | 1179 | — |
| 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid | — | 1392 | — |
| 1-Dimethylaminomethyl-1-methylpropyl benzoate (amylocaine) and its salts | — | 50 | — |
| 1-Ethyl-1-methylmorpholinium bromide | — | 1084 | — |
| 1-Ethyl-1-methylpyrrolidinium bromide | — | 1091 | — |
| 1-Hydroxy-2,4-diaminobenzene (2,4-Diaminophenol) and its dihydrochloride salts (2,4-Diaminophenol HCl) when used as a substance in hair dye products | — | 1338 | — |
| 1-Hydroxy-4-(p-toluidino)anthraquinone (Solvent Violet 13; CI 60725) when used as a substance in hair dye products | — | 1363 | — |
| 1-Methoxy-2,4-diaminobenzene (2,4-Diaminoanisole - CI 76050) and its salts | — | 376 | — |
| 1-Methoxy-2,5-diaminobenzene (2,5-Diaminoanisole) and its salts | — | 377 | — |
| 1-Methyl-2,4,5-trihydroxybenzene and its salts, when used as a substance in hair dye products | — | 1244 | — |
| 1-Methyl-3-nitro-1-nitrosoguanidine | — | 702 | — |
| 1-Vinyl-2-pyrrolidone | — | 1113 | — |
| 1-Vinylimidazole | — | 1622 | — |
Showing 100 of 1758 ingredients
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