2,4-DIAMINOPHENOXYETHANOL HCL
HAIR DYEING · CAS 66422-95-5 · EC 266-357-1
Chemical identification
- INCI
- 2,4-DIAMINOPHENOXYETHANOL HCL
- Chemical name
- 2-(2,4-diaminophenoxy)ethanol dihydrochloride
- IUPAC
- 2,4-Diaminophenoxyethanol, its hydrochloride and its sulphate
- CAS
- 66422-95-5
- EC / EINECS
- 266-357-1
- Trade synonyms
- 41574 · 84411 · 87654
EU regulatory status
- Reference
- III/242
- Maximum concentration
- —
- Other conditions
- For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 2,0 % (as hydrochloride) (b) For professional use only.
- Warnings
- (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (b) To be printed on the label: The mixing ratio.“For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them.”
- CMR
- Not classified
- Last CosIng update
- 2014-02-14
Recent analyses mentioning this ingredient
Sin análisis publicados todavía para este ingrediente.
Other Annex III items
- 1,3-BIS-(2,4-DIAMINOPHENOXY)PROPANE
- 1,5-NAPHTHALENEDIOL
- 1-HEXYL 4,5-DIAMINO PYRAZOLE SULFATE
- 1-NAPHTHOL
- 2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE
- 2,6-DIAMINOPYRIDINE
- 2,6-DIHYDROXY-3,4-DIMETHYLPYRIDINE
- 2,6-DIHYDROXYETHYLAMINOTOLUENE
Technical function
This ingredient is classified as:
About Annex III of Regulation (EC) No 1223/2009
Annex III of Regulation (EC) No 1223/2009 lists the substances that may be used in cosmetic products only under specific conditions defined by the European legislator. For each entry, the annex establishes the maximum permitted concentration, the product categories in which use is authorised (rinse-off or leave-on, use on children, etc.), the applicable additional conditions, and the mandatory labelling warnings that the manufacturer must include. A prior safety assessment by the SCCS is a prerequisite for any modification to this list. Restrictions may vary depending on the area of application — hair, skin, mucous membranes — and the target population — adults, children under three years of age. BD-API allows Responsible Persons to verify in real time whether their formulations comply with the current conditions of Annex III, integrating CosIng information into their audit workflows. Explore the full Annex III →
Restriction conditions like these change
A new maximum concentration or product-type condition turns a compliant formula into a non-compliant one overnight. BD-API delivers every Annex III change to your system via API, webhooks and automated alerts.
Data source: Official CosIng from the European Commission, updated on 9 April 2026. Learn more →