Chemical identification
- INCI
- O-PHENYLPHENOL
- Chemical name
- Biphenyl-2-ol
- IUPAC
- Biphenyl-2-ol
- CAS
- 90-43-7
- EC / EINECS
- 201-993-5
- Trade synonyms
- 28130
EU regulatory status
- Reference
- V/7
- Maximum concentration
- (a) 0,2 % (as phenol (b) 0,15 % (as phenol)
- Other conditions
- When o-Phenylphenol and Sodium o-Phenylphenate are used together, the combined concentration (as phenol) shall not exceed 0,2 % in rinse-off and 0,15 % in leave-on products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products.
- Warnings
- Avoid contact with eyes.
- CMR
- Not classified
- Last CosIng update
- 2026-01-15
Recent analyses mentioning this ingredient
- SeguimientoOpinión científica SCCS · 25 de octubre de 2024SCCS Opinion on Biphenyl-2-ol and Sodium 2-biphenylolate used in cosmetic products (CAS/EC No. 90-43-7/201-993-5 and 132-27-4/205-055-6)
El SCCS confirmó que Biphenyl-2-ol (o-Phenylphenol, OPP) y Sodium 2-biphenylolate (SOPP) son seguros como conservantes al 0.15% leave-on y 0.2% rinse-off, incluso considerando su clasificación como Carcinógeno Cat. 2. Si tu empresa usa OPP o SOPP como conservantes, las concentraciones actuales del Anexo V se mantienen. La Comisión deberá adoptar medidas regulatorias formales dentro de los 15 meses posteriores a la clasificación CLP final de la sustancia; monitoreá los plazos de la clasificación oficial.
Other Annex V items
- 2-BROMO-2-NITROPROPANE-1,3-DIOL
- 5-BROMO-5-NITRO-1,3-DIOXANE
- 7-ETHYLBICYCLOOXAZOLIDINE
- BENZETHONIUM CHLORIDE
- BENZYL ALCOHOL
- BENZYLHEMIFORMAL
- BROMOCHLOROPHENE
- CHLOROBUTANOL
Technical function
This ingredient is classified as:
About Annex V of Regulation (EC) No 1223/2009
Annex V of Regulation (EC) No 1223/2009 lists the preservatives authorised for use in cosmetic products in the European Union. Only preservatives included in this annex may be used to inhibit the development of micro-organisms in cosmetics. Each entry defines the maximum permitted concentration, the product categories in which it may be used, the applicable specific conditions, and any mandatory labelling warnings. Modifications to this annex are published periodically in the Official Journal of the EU following an opinion from the SCCS (Scientific Committee on Consumer Safety) and are automatically reflected in this database. BD-API synchronises these updates on a continuous scheduled basis and allows manufacturers and Responsible Persons to verify in real time whether their formulations comply with the current conditions of Annex V, integrating CosIng information into their audit and quality control workflows. Explore the full Annex V →
Positive lists are tightly governed
New SCCS opinions and amending regulations reshape this Annex regularly — an entry that changes must be reflected in your active formulations. BD-API delivers every change to your system via API, webhooks and automated alerts.
Data source: Official CosIng from the European Commission, updated on 9 April 2026. Learn more →